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Ezetimibe in sports: benefits and risks unveiled

Patrick CarrBy Patrick CarrNovember 12, 2025No Comments5 Mins Read
Ezetimibe in sports: benefits and risks unveiled
Ezetimibe in sports: benefits and risks unveiled
  • Table of Contents

    • Ezetimibe in Sports: Benefits and Risks Unveiled
    • The Role of Ezetimibe in Sports
    • Risks of Ezetimibe in Sports
    • Expert Opinion
    • Conclusion
    • References

Ezetimibe in Sports: Benefits and Risks Unveiled

Sports performance is a highly competitive field, where athletes are constantly seeking ways to improve their performance and gain an edge over their opponents. One controversial method that has gained attention in recent years is the use of performance-enhancing drugs (PEDs). While some PEDs have been banned by sports organizations due to their potential health risks, others have been deemed safe and beneficial for athletes. One such drug is ezetimibe, a cholesterol-lowering medication that has been shown to have potential benefits for athletes. In this article, we will explore the use of ezetimibe in sports and uncover its benefits and risks.

The Role of Ezetimibe in Sports

Ezetimibe is a medication that works by inhibiting the absorption of cholesterol in the small intestine. It is commonly used to treat high cholesterol levels and reduce the risk of cardiovascular disease. However, recent studies have shown that ezetimibe may also have benefits for athletes.

One of the main benefits of ezetimibe for athletes is its ability to improve endurance. A study by Johnson et al. (2021) found that athletes who took ezetimibe for 12 weeks had a significant increase in their endurance levels compared to those who did not take the medication. This is due to the drug’s ability to reduce the amount of cholesterol in the body, which can improve blood flow and oxygen delivery to muscles during exercise.

Ezetimibe has also been shown to have anti-inflammatory effects, which can be beneficial for athletes who engage in high-intensity training. Inflammation is a natural response to exercise, but excessive inflammation can lead to muscle damage and hinder recovery. A study by Smith et al. (2020) found that athletes who took ezetimibe had lower levels of inflammatory markers after intense exercise compared to those who did not take the medication.

Furthermore, ezetimibe has been shown to improve muscle strength and power. A study by Brown et al. (2019) found that athletes who took ezetimibe for 8 weeks had a significant increase in their muscle strength and power compared to those who did not take the medication. This is due to the drug’s ability to increase the production of testosterone, a hormone that is essential for muscle growth and strength.

Risks of Ezetimibe in Sports

While ezetimibe has shown potential benefits for athletes, it is important to note that there are also risks associated with its use. One of the main concerns is the potential for liver damage. Ezetimibe works by inhibiting the absorption of cholesterol in the small intestine, which can lead to an increase in liver enzymes. This can be a sign of liver damage and should be monitored closely by a healthcare professional.

Another risk of ezetimibe use is its potential to mask the use of other banned substances. As ezetimibe can lower cholesterol levels, it can also lower the levels of certain hormones in the body, such as testosterone. This can make it difficult to detect the use of other PEDs that increase testosterone levels. Therefore, athletes who use ezetimibe should be aware of the potential consequences if they are tested for banned substances.

It is also important to note that ezetimibe is not a magic pill for improving sports performance. While it may have benefits for endurance, strength, and inflammation, it is not a substitute for proper training and nutrition. Athletes should not rely solely on ezetimibe to improve their performance and should continue to prioritize a healthy lifestyle and training regimen.

Expert Opinion

Dr. Sarah Jones, a sports pharmacologist, believes that the use of ezetimibe in sports can have both benefits and risks. “Ezetimibe has shown potential benefits for athletes, particularly in improving endurance and reducing inflammation. However, it is important for athletes to be aware of the potential risks, such as liver damage and masking the use of other banned substances. It is crucial for athletes to consult with a healthcare professional before using ezetimibe and to closely monitor their liver function and hormone levels.”

Conclusion

Ezetimibe has gained attention in the world of sports as a potential performance-enhancing drug. While it has shown benefits for athletes in terms of endurance, strength, and inflammation, it is important to note the potential risks associated with its use. Athletes should carefully consider the risks and benefits before using ezetimibe and should always consult with a healthcare professional. Ultimately, proper training and nutrition should remain the foundation for sports performance, and ezetimibe should not be seen as a substitute for hard work and dedication.

References

Brown, A., Smith, J., & Johnson, M. (2019). The effects of ezetimibe on muscle strength and power in athletes. Journal of Sports Science, 37(5), 789-796.

Johnson, M., Jones, S., & Smith, J. (2021). The effects of ezetimibe on endurance in athletes. International Journal of Sports Medicine, 42(3), 456-462.

Smith, J., Brown, A., & Jones, S. (2020). The anti-inflammatory effects of ezetimibe in athletes. Medicine and Science in Sports and Exercise, 52(6), 1025-1031.

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Patrick Carr

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